| YEAR | TITLE | ROLE |
| 2012 | Dark Shadows | Barbanas Collins |
| 2011 | Pirates of the Caribbean : On Stranger Tides | Jack Sparrow |
| 2011 | The Rum Diary | Paul Kemp |
| 2011 | Rango | Rango |
| 2010 | The Tourist | Frank Tupelo |
| 2010 | Alice in Wonderland | Mad Hatter |
| 2009 | Public Enemies | John Dillinger |
| 2009 | The Imaginarium of Doctor Parnassus | Imaginarium Tony 1 |
| 2009 | SpongeBob SquarePants (TV Series) | Jack Kahuna Laguna |
| 2007 | Sweeney Todd: The Demon Barber of Fleet Street | Sweeney Todd |
| 2007 | Pirates of the Caribbean: At World’s End | Jack Sparrow |
| 2006 | Pirates of the Caribbean: Dead Man’s Chest | Jack Sparrow |
| 2005 | Corpse Bride | Victor van Dort |
| 2005 | Charlie and the Chocolate Factory | Willy Wonka |
| 2004 | The Libertine | Rochester |
| 2004 | Finding Neverland | Sir James Matthew Barrie |
| 2004 | …And They Lived Happily Ever After | L’inconnu |
| 2004 | King of the Hill (TV Series) | Yogi Victor |
| 2004 | Secret Window | Mort Rainey |
| 2003 | Once Upon a Time in Mexico | Sands |
| 2003 | Pirates of the Caribbean: The Curse of the Black Pearl | Jack Sparrow |
| 2001 | From Hell | Inspector Frederick Abberline |
| 2001 | Blow | George Jung |
| 2000 | The Fast Show (TV Series) | Customer in suit store |
| 2000 | Chocolat | Roux |
| 2000 | Before Night Falls | Bon Bon / Lieutenant Victor |
| 2000 | The Man Who Cried | Cesar |
| 1999 | Sleepy Hollow | Ichabod Crane |
| 1999 | The Astronaut’s Wife | Commander Spencer Armacost |
| 1999 | The Ninth Gate | Dean Corso |
| 1998 | Fear and Loathing in Las Vegas | Raoul Duke |
| 1997 | The Brave | Raphael |
| 1997 | Donnie Brasco | Donnie Brasco / Joseph D. ‘Joe’ Pistone |
| 1995 | Nick of Time | Gene Watson |
| 1995 | Dead Man | William Blake |
| 1994 | Don Juan DeMarco | Don Juan |
| 1994 | Ed Wood | Ed Wood |
| 1993 | What’s Eating Gilbert Grape | Gilbert Grape |
| 1993 | Benny & Joon | Sam |
| 1993 | Arizona Dream | Axel Blackmar |
| 1991 | Freddie’s Dead: The Final Nightmare | Guy on TV |
| 1990 | Edward Scissorhands | Edward Scissorhands |
| 1990 | Cry-Baby | Cry-Baby |
| 1987-1990 | 21st Jump Street | Officer Tom Hanson |
| 1987 | Hotel (TV Series) | Rob Cameron |
| 1986 | Platoon | Lerner |
| 1986 | Slow Burn (TV Series) | Donnie Fleischer |
| 1985 | Lady Blue (TV Series) | Lionel Viland |
| 1985 | Private Resort | Jack |
| 1984 | A Nightmare of Elm Street | Glen Lantz |
|
POTC: On Stranger Tides (2011) 
The Rum Diary (2011) 
Rango (2011) 
The Tourist (2010) 
